Evolugate

Evolugate is a private biotechnology company founded in 2005 in Gainesville, Florida that developed a patented adaptive-evolution platform to optimize microorganisms such as bacteria, yeasts, algae, fungi, and archaea for industrial applications. The company has positioned its technology as a way to improve microbial growth, stress tolerance, substrate utilization, and production yield across sectors including pharmaceuticals, probiotics, biopesticides, agronomy, green chemistry, and bioremediation. In healthcare-related applications, Evolugate has highlighted the use of its platform to improve bacterial host strains for plasmid DNA production, a manufacturing bottleneck relevant to nucleic acid vaccines and gene therapies. The business appears to have been primarily a technology and licensing company rather than a developer of a conventional therapeutic pipeline. Public business registry records indicate the Florida registration was revoked in September 2025 for failure to file an annual report, so the company does not appear to be currently active as a going concern under that registration.