Company intelligence / Profile preview
Evox Therapeutics
Oxford, England, United Kingdomevoxtherapeutics.com ↗
- Ownership
- Private
- Development stage
- Preclinical
01
Overview
Evox has demonstrated robust preclinical proof-of-concept data showing efficient CNS delivery and functional activity of exosome-loaded CRISPR editors, mRNAs, proteins, and RNAi agents. In vivo rodent studies show high levels of gene recombination or silencing after direct CNS injection. The company’s lead programs are advancing toward first-in-human trials targeting severe rare neurological disorders.
- Therapeutic areas
- Metabolic DisordersRare DiseasesNeurology
- Modalities
- Exosome-based therapeutics (engineered extracellular vesicles)Genome editing (CRISPR/Cas-based)mRNA deliveryProtein replacement therapyRNAi/siRNA/shRNA delivery
- Industry
- Biotech
02
Drug pipeline
11 assets10 more assets in the full pipeline.
03
Partnerships
Takeda Pharmaceutical Company Limited – multi-target collaboration on up to five rare disease therapies using Evox’s technology. Takeda assumes responsibility for clinical development of certain partnered programs.Eli Lilly – research partnership focused on five neurology targets with significant upfront payments and potential milestones totaling over $1 billion.
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