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Preclinical vaccine demonstrates protection against multiple antibiotic-resistant Gram-positive bacteria (e.g., MRSA, VRE), Gram-negative bacteria (e.g., ESBL E. coli, CR Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa), and fungi (e.g., Candida albicans, mucormycosis) in mouse models of blood and lung infections, with efficacy within 24 hours lasting up to 28 days.
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