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F2G

Macclesfield/Near Alderley Park, Cheshire, United Kingdomf2g.com ↗

Ownership: Private
Development stage: Phase 3

Overview

Olorofim, the lead compound, has shown promise as a first-in-class antifungal with activity against rare and resistant fungal pathogens. It has received orphan drug status from the EMA for invasive aspergillosis and scedosporiosis. Clinical studies are ongoing to support registration. The company recently raised $100M to complete late-stage testing and pursue FDA approval. Both IV and oral formulations are being developed; early data suggest a favorable safety profile. The orotomide class offers a novel mechanism distinct from existing antifungals.

Therapeutic areas: Infectious Diseases
Modalities: Small molecules (orotomides)
Industry: Biotech

Drug pipeline

4 assets

olorofim

3 more assets in the full pipeline.

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Partnerships

European Investment Bank/EU InnovFin Infectious Diseases Finance Facility/Horizon2020 funding support for R&D/clinical trials of Olorofim

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