FailSafeTM iPSC

FailSafe Biotech is a regenerative medicine company focused on developing a universal safety system for cell-based therapies. The company's proprietary FailSafe™ technology involves the integration of a suicide gene (Herpes Simplex Virus Thymidine Kinase) into the cell's genome, linked to a cell-cycle essential gene. This linkage ensures that any cell that loses the safety switch or begins to proliferate uncontrollably (such as forming a tumor) will die, while allowing for the selective elimination of the transplanted cells if necessary. By addressing the primary safety concern of tumorigenicity in induced pluripotent stem cell (iPSC) therapies, FailSafe Biotech aims to enable the broad clinical application of next-generation regenerative medicines.