Company intelligence / Profile preview
Fibrex Medical Inc.
- Ownership
- Private
- Development stage
- Phase 2
Overview
FX06 demonstrated positive Phase II results for reducing myocardial necrosis following acute myocardial infarction. The peptide showed statistically significant efficacy compared to placebo in the FIRE study with over 230 patients. FX06 binds VE-cadherin to inhibit tissue inflammation/injury and preserve endothelial barrier function. Further development was planned via partnership with Ikaria Holdings.
“FX06 has demonstrated efficacy in this Phase II trial... can provide clinical benefit by preventing reperfusion injury for the huge number of patients who survive heart attacks each year.” — Dr. Rainer Henning, President & CEO
After licensing the portfolio to Ikaria Holdings in August 2009—including all preclinical/clinical development and commercialization rights—Fibrex ceased independent product development.
- Therapeutic areas
- CardiovascularImmunology
- Modalities
- PeptidesPeptidomimetic compounds
- Industry
- Biotech
Drug pipeline
2 assets1 more asset in the full pipeline.
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