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Filkri is an early-stage biotechnology company focused on developing next-generation inhibitors for KRAS-driven cancers. The company is specifically working on novel small molecule approaches to target KRAS mutations that have remained elusive to first-generation inhibitors. By leveraging advanced medicinal chemistry, Filkri aims to expand the therapeutic window and overcome resistance mechanisms commonly seen in KRAS-mutant solid tumors. Their current research is centered on optimizing lead candidates for non-small cell lung cancer and gastrointestinal malignancies.
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