Company intelligence / Profile preview

Flamingo Therapeutics

Leuven, Flemish Brabant, Belgiumflamingotx.com ↗
Ownership
Private
Development stage
Phase 2
01

Overview

Flamingo Therapeutics has advanced its lead antisense oligonucleotide danvatirsen into a randomized international Phase II trial in combination with pembrolizumab for recurrent/metastatic head and neck squamous cell carcinoma. Early results show clinical activity. A separate investigator-led Phase I study evaluates danvatirsen as monotherapy and with venetoclax in relapsed/refractory AML/MDS. The company’s second asset, FLM‑7523 targeting MALAT1 lncRNA, is IND-ready to enter first-in-human studies targeting solid tumors.

Therapeutic areas
OncologyHematology
Modalities
Antisense oligonucleotides (ASOs)RNA-targeted therapies
Industry
Biotech
02

Drug pipeline

7 assets

danvatirsen

2

6 more assets in the full pipeline.

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03

Partnerships

Merck & Co., Inc. – using pembrolizumab/KEYTRUDA® as combination partner in clinical trials.Ionis Pharmaceuticals – original discoverer of danvatirsen licensed to Flamingo.Academic partnerships with Montifore Einstein Comprehensive Cancer Center and MD Anderson Cancer Center on investigator-led trials.

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