Company intelligence / Profile preview
Flare Therapeutics
Cambridge, Massachusetts, United Statesflaretx.com ↗
- Ownership
- Private
- Employees
- ~75
- Development stage
- Phase 1
01
Overview
Flare Therapeutics has entered the clinic with its lead asset FX‑909—a first-in-class orally bioavailable small molecule inhibitor of PPARG—currently being evaluated in a Phase I study for patients with advanced solid malignancies including locally advanced or metastatic urothelial carcinoma. The ongoing trial assesses safety, tolerability, pharmacokinetics/dynamics and preliminary efficacy. Preclinical data showed robust anti-tumor activity and favorable safety profile. No clinical efficacy results have been published yet as the study remains ongoing.
- Therapeutic areas
- OncologyMetabolic Disorders
- Modalities
- small molecules
- Industry
- Biotech
02
Drug pipeline
4 assets3 more assets in the full pipeline.
Request access →03
Partnerships
Roche – strategic discovery collaboration to develop novel small molecule drugs against previously undrugged transcription factor targets in oncology; deal includes $70M upfront payment plus milestones/royalties potentially exceeding $1.8B.Caris Life Sciences – partnership for molecular profiling/biomarker-driven patient selection and companion diagnostics development support.
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