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Flatley Discovery Lab

Charlestown, Massachusetts, United Statesflatleydiscoverylab.com ↗

Ownership: Private
Employees: ~30
Development stage: Other

Overview

Flatley Discovery Lab is a nonprofit research organization focused on discovering and developing small molecule therapeutics for cystic fibrosis. Its lead programs, FDL169 and FDL176, are CFTR modulators that reached Phase 1/2 clinical trials but are currently suspended. Preclinical data showed significant restoration of chloride transport in CF models and promising safety profiles in animal studies.

Therapeutic areas: Pulmonology
Modalities: Small molecule
Industry: Academic Hospital/University/Research

Partnerships

Woods Hole Oceanographic Institution (WHOI) – collaboration to screen marine natural products for novel CF therapeutics

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