Company intelligence / Profile preview
Foghorn Therapeutics
- Ownership
- Public · FHTX
- Employees
- ~100
- Development stage
- Other
Overview
Foghorn Therapeutics has advanced its lead candidate, the oral selective SMARCA2 inhibitor FHD‑909, into a Phase 1 trial for patients with SMARCA4-mutated cancers—primarily non-small cell lung cancer. Early clinical responses have been observed in other programs such as the AML study of FHD‑286 but did not meet internal efficacy thresholds to continue independently. The company’s pipeline includes several preclinical assets targeting chromatin regulatory proteins such as ARID1B, CBP, and EP300. Preclinical data support further exploration of these agents both as monotherapies and in combination regimens. The company maintains a strong cash position supporting operations into at least late 2026 or early 2027.
- Therapeutic areas
- Oncology
- Modalities
- Small molecules (inhibitors and degraders)Precision therapeutics targeting gene expression/chromatin regulatory system
- Industry
- Biotech
Drug pipeline
8 assets7 more assets in the full pipeline.
Partnerships
Financials
- Market cap
- $113.1M
- Total revenue
- $30.9M
- Enterprise value
- $-11.4M
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