Foreground Systems

Foreground is a functional genomics company building a platform to map the functional impact of every genetic variant in the human genome. By combining high-throughput CRISPR screening with advanced computational biology, the company aims to solve the "variant-to-function" challenge in human genetics. Their platform identifies the specific genes and pathways regulated by disease-associated genetic variants, providing a roadmap for the development of precision medicines. Foreground's approach focuses on discovering novel, genetically-validated targets for complex diseases with high unmet needs. The company was incubated by Atlas Venture and is based on pioneering research from the Engreitz Lab at Stanford University.