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Foreland Pharma’s lead asset FP‑208, a dual PI3K/mTOR inhibitor, has completed a Phase I clinical trial evaluating safety, tolerability, pharmacokinetics, and preliminary efficacy in patients with advanced solid tumors. The study confirmed safety and provided initial signals of anti-tumor activity. Another program targeting Sphingosine 1-phosphate receptors (FP‑253/FP‑264) remains at the preclinical stage.
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