carboxyamidotriazole
Pre-clinical- Indications
- Diabetic retinopathy, Age-related macular degeneration, Retinal neovascular disease
Company intelligence / Profile preview
Developing a novel long-acting ORAI1 blocker that acts both upstream and downstream of VEGF inhibition for durable administration up to 12 months to treat retinal neovascular disease. The compound has been administered to over 900 patients systemically for cancer treatment, potentially allowing more rapid progress to Phase 2 once IND enabling ocular toxicity testing is completed.
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