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The Fujian Institute of Microbiology (FIM) is a specialized research and development institution focused on microbial biotechnology and the discovery of bioactive natural products. Established in 1958 and based in Fuzhou, China, the institute excels in the screening, strain improvement, and large-scale fermentation of microbial metabolites. FIM is historically significant for its role in developing gentamicin and has since become a leader in the production and optimization of immunosuppressants like sirolimus (rapamycin) and various macrolide antibiotics. The institute operates comprehensive facilities for both upstream microbial engineering and downstream chemical synthesis, providing technical services and products to the global pharmaceutical and agricultural sectors.
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