Company intelligence / Profile preview
Fulcrum Therapeutics
Cambridge, Massachusetts, United States
- Ownership
- Public · FULC
- Employees
- ~150
- Development stage
- Phase 2
01
Overview
The lead program pociredir (FTX-6058) for sickle cell disease has completed enrollment in the Phase 1b PIONEER trial's 12 mg dose cohort with data expected early Q3 2025; the higher dose cohort enrollment started. Pociredir aims to increase fetal hemoglobin levels potentially transforming SCD treatment with an oral once-daily therapy. The FSHD program losmapimod was discontinued after a failed Phase 3 trial but data from this study are being shared openly with the FSHD research community[5][6][7].
- Therapeutic areas
- HematologyNeurology
- Modalities
- Small molecules
- Industry
- Biotech
02
Drug pipeline
4 assets3 more assets in the full pipeline.
Request access →03
Partnerships
Sanofi – collaboration and licensing agreement for losmapimod commercialization outside the U.S.[7]
04
Financials
- Market cap
- $289.9M
- Total revenue
- $0
- Enterprise value
- $-23.6M
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