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Galecto, Inc.

Ownership: Public · GLTO
Employees: ~5
Development stage: Phase 2

Overview

Galecto has advanced multiple small molecule candidates into clinical development. GB1211, an oral galectin‑3 inhibitor, entered a Phase 2 trial in combination with pembrolizumab for metastatic melanoma and HNSCC in Q2 2024. BRM‑1420, a novel dual ENL-YEATS/FLT3 inhibitor for AML with activity in MLLr and NPM1c genetic subsets, was added to the pipeline in October 2024 based on promising preclinical data. Other programs include GB0139 for fibrotic lung disease and GB2064 targeting LOXL2[1][2][3].

Therapeutic areas: ImmunologyOncologyPulmonologyGastroenterology
Modalities: small molecules
Industry: Biotech

Drug pipeline

6 assets

GB0139

5 more assets in the full pipeline.

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Partnerships

Investigator-led trial at Providence Portland Medical Center’s Earle A. Chiles Research Institute; no major pharma partnerships disclosed as of May 2025[2]

Financials

Market cap: $34.5M
Total revenue: $0
Enterprise value: $-506M

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