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Company intelligence / Profile preview
Galecto has advanced multiple small molecule candidates into clinical development. GB1211, an oral galectin‑3 inhibitor, entered a Phase 2 trial in combination with pembrolizumab for metastatic melanoma and HNSCC in Q2 2024. BRM‑1420, a novel dual ENL-YEATS/FLT3 inhibitor for AML with activity in MLLr and NPM1c genetic subsets, was added to the pipeline in October 2024 based on promising preclinical data. Other programs include GB0139 for fibrotic lung disease and GB2064 targeting LOXL2[1][2][3].
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