Company intelligence / Profile preview

Gene Signal International SA

Lausanne, Vaud, Switzerlandorpha.net ↗
Ownership
Private
Development stage
Phase 3
01

Overview

Gene Signal developed a pipeline focused on modulating angiogenesis using antisense oligonucleotides, proteins, and monoclonal antibodies. Its lead product, aganirsen (GS‑101), an antisense oligonucleotide eye drop for neovascular-associated corneal graft rejection (NV-CGR), completed or nearly completed Phase III trials by 2013. Additional programs were in Phase II or discovery for other ophthalmic and vascular indications. The company has demonstrated preclinical efficacy in models of retinal neovascular disease and ischemic retinopathy.

Therapeutic areas
OphthalmologyOncologyCardiovascularDermatology
Modalities
Antisense oligonucleotidesProteinsMonoclonal antibodies
Industry
Biotech
02

Drug pipeline

1 asset

aganirsen

3
03

Partnerships

No major pharmaceutical partnerships publicly disclosed as of last available information. The company expressed intent to seek pharma partners for further development/commercialization.

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