Genetic Chemistry

Genetic Chemistry is a San Diego-based biotechnology company specializing in the development of immunopharmacotherapies and vaccines for substance use disorders and infectious diseases. Founded by Dr. Kim Janda, a pioneer in the field of chemical biology at The Scripps Research Institute, the company focuses on creating vaccines that induce the production of antibodies against small molecules such as fentanyl, heroin, and nicotine. These antibodies are designed to sequester the target drug in the bloodstream, preventing it from crossing the blood-brain barrier and thereby blocking its physiological and addictive effects. Genetic Chemistry's lead programs, including a fentanyl vaccine, aim to provide a novel therapeutic approach to the opioid crisis by preventing overdose and supporting long-term recovery. The company also leverages its expertise in DNA-encoded libraries and hapten-protein conjugation to address challenges in oncology and antimicrobial resistance.