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Genometry

Cambridge (Kendall Square), Massachusetts, United States

Ownership: Private
Development stage: Other

Overview

Genometry commercialized the L1000 assay, a high-throughput gene-expression profiling technology developed at the Broad Institute. The platform measures approximately 1,000 landmark genes to accurately estimate the activity of all ~20,000 genes expressed in a cell, operating at a fraction of the cost of conventional methods (a few dollars per sample versus $500)[2]. The assay enables pharmaceutical companies to rapidly screen and characterize large compound libraries, with applications in drug discovery, hit selection, and compound prioritization[2].

Modalities: Assay-based service platform (not a traditional drug modality)
Industry: Drug Discovery Services

Partnerships

Janssen Pharmaceutica (multiyear contract to generate gene-expression profiles for 250,000 compounds)A dozen pharmaceutical firms and other companies using the assay

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