Genotypic Resistance Guided Therapy

SpeeDx is a molecular diagnostics company that specializes in multiplex real-time polymerase chain reaction (qPCR) solutions for infectious diseases. The company is a pioneer in "Resistance Guided Therapy," a clinical approach that uses genotypic information to identify both the pathogen and its antibiotic resistance profile simultaneously. This allows clinicians to prescribe the most effective treatment immediately, improving patient outcomes and supporting antimicrobial stewardship. Their flagship products include the ResistancePlus and PlexPCR suites, which target sexually transmitted infections like Mycoplasma genitalium and Gonorrhea. SpeeDx's proprietary technologies, PlexPrime and PlexZyme, enable high-level multiplexing and sensitive detection of single nucleotide polymorphisms (SNPs) associated with drug resistance.