Company intelligence / Profile preview

GenSight Biologics

Ownership
Public · SIGHT
Employees
~16
Development stage
Phase 3
01

Overview

GenSight Biologics’ lead candidate LUMEVOQ® has completed three Phase III trials for LHON caused by ND4 mutations, showing significant and sustained visual function improvement compared to natural history. The company is planning an additional Phase III trial after regulatory feedback. GS030, their optogenetic gene therapy for retinitis pigmentosa, is showing efficacy signals in ongoing Phase I/II studies. CMC challenges have been addressed for LUMEVOQ®, with new regulatory submissions planned.

Therapeutic areas
Ophthalmology
Modalities
Gene therapyRecombinant proteinOptogenetics-based therapy
Industry
Biotech
02

Drug pipeline

2 assets

lenadogene nolparvovec

3

1 more asset in the full pipeline.

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03

Partnerships

Academic license agreements with Sorbonne Université, CNRS, Inserm & SATT LutechInserm Transfert S.A.GenethonHarvard UniversityMassachusetts Institute of TechnologyNovartis Pharma AGAdverum Biotechnologies

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