Gillies McIndoe Research Institute

The Gillies McIndoe Research Institute (GMRI) is a New Zealand-based non-profit research organization focused on regenerative medicine and cancer treatment. The institute specializes in the study of the Renin-Angiotensin System (RAS) and its role in regulating cancer stem cells across various tumors and vascular malformations. By repurposing off-patent medications to target these stem cells, GMRI aims to develop low-toxicity, cost-effective therapies for conditions such as glioblastoma multiforme and infantile hemangioma. Their research extends into fibrotic conditions and organ regeneration, leveraging a unique understanding of stem cell niches. The institute's work is characterized by a bench-to-bedside approach, moving fundamental biological discoveries into clinical applications.