Gloriana Therapeutics

Gloriana Therapeutics was a private Rhode Island biotechnology company focused on implantable encapsulated-cell neurotherapeutics for neurological disorders. The company, formerly known as NsGene, developed devices containing engineered human cells designed to secrete neurotrophic factors directly into target tissue in the central nervous system. Its disclosed programs and publications point to applications in Alzheimer's disease, Parkinson's disease, epilepsy, neuropathic pain, and sensorineural hearing loss, with a notable preclinical Alzheimer's program using BDNF delivered to the hippocampus through its CytoReactor implant. Available evidence indicates the company remained preclinical and is now closed or out of business rather than acquired.