Company intelligence / Profile preview

Greenstone Biosciences

Palo Alto, California, USAgreenstonebio.com ↗
Ownership
Private
Employees
~20
Development stage
Preclinical
01

Overview

Greenstone Biosciences leverages a proprietary AI-driven platform combined with the world’s largest repository of patient-derived iPSC lines to accelerate drug discovery. The company has contributed to landmark studies identifying new therapeutic strategies for cardiac fibrosis and developed advanced tools for early cardiotoxicity detection. Their approach enables more precise modeling of human disease biology and pharmacogenomic variation, supporting both internal pipeline development and collaborations with academic partners worldwide. Recent preclinical results include successful reversal of cardiac fibrosis in engineered tissues and animal models by targeting SRC kinase pathways; their Genistein-based therapy has reached Phase 1/2 clinical evaluation in heart failure patients.

Therapeutic areas
Cardiovascular
Modalities
Small moleculesInduced pluripotent stem cells (iPSC)-based therapeutics and models
Industry
Biotech
02

Drug pipeline

3 assets

GSB D100

Preclinical

2 more assets in the full pipeline.

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03

Partnerships

Collaborations with Stanford University School of Medicine/Cardiovascular Institutesupported by NIH grantspartnerships with leading academic institutions globally.

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