Company intelligence / Profile preview
Grey Wolf Therapeutics
Oxford, Oxfordshire, United Kingdomgreywolftherapeutics.com ↗
- Ownership
- Private
- Employees
- ~75
- Development stage
- Phase 1
01
Overview
Grey Wolf’s lead asset GRWD5769 has delivered strong results in a Phase 1/2 oncology trial demonstrating proof-of-mechanism and target engagement. The company’s second program GRWD0715 is advancing through preclinical development for autoimmune indications. The company leverages its proprietary antigen modulation platform to address immune dysfunction in oncology and autoimmunity by inhibiting ERAP enzymes to alter antigen presentation on diseased cells. Initial data from ongoing trials are being presented at major scientific meetings such as ASCO in 2024.
- Therapeutic areas
- OncologyImmunologyInfectious Diseases
- Modalities
- Small molecules (notably ERAP1 and ERAP2 inhibitors)MHC Class I-directed therapies (including soluble T cell receptor [TCR] and TCR mimic bispecifics)
- Industry
- Biotech
02
Drug pipeline
4 assets3 more assets in the full pipeline.
03
Partnerships
Pfizer Ventures (investor)collaborations with University of Oxford, Monash University, University of SouthamptonSygnature Discovery as CRO partner
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