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GRI Bio is conducting a Phase 2a study of GRI-0621, an iNKT cell inhibitor, for idiopathic pulmonary fibrosis. Interim biomarker and safety data are expected in 2024. GRI-0803, for SLE, aims to enter Phase 1 trials in late 2024. Preclinical data for NKT modulators show anti-inflammatory effects in multiple autoimmune models.
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