Company intelligence / Profile preview
Gritstone bio, Inc.
Emeryville, California, United States
- Ownership
- Private
- Employees
- ~231
- Development stage
- Phase 1
01
Overview
Gritstone’s lead program GRANITE showed positive preliminary progression-free survival data in a randomized Phase II trial for front-line MSS colorectal cancer. The company demonstrated the ability to manufacture personalized vaccines at scale and observed encouraging trends favoring GRANITE over standard of care. Its COVID SAM vaccine candidate showed strong preclinical immunogenicity data but did not reach late-stage clinical development. The company also advanced an off-the-shelf SLATE immunotherapy and partnered with major pharma on infectious disease programs.
- Therapeutic areas
- OncologyInfectious Diseases
- Modalities
- self-amplifying mRNA vaccines (SAM)adenoviral vectorspersonalized neoantigen cancer vaccinesoff-the-shelf shared neoantigen immunotherapies
- Industry
- Biotech
02
Drug pipeline
20 assets19 more assets in the full pipeline.
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Partnerships
Bristol Myers Squibb – collaboration on GRANITE with checkpoint inhibitors nivolumab/ipilimumabbluebird bio – strategic collaborationGenevant Sciences GmbH – license agreementGilead Sciences – collaboration on HIV therapeutic vaccines using SAM/adeno vector platforms
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