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GW Pharmaceuticals successfully commercialized Sativex for spasticity due to multiple sclerosis (approved in >25 countries) and Epidiolex for seizures in Lennox-Gastaut, Dravet syndrome, and tuberous sclerosis complex (FDA and EMA approved). Other programs, such as GWP42006 (cannabidivarin), had mixed clinical results in epilepsy and autism spectrum disorders. The pipeline has ongoing late-stage programs in additional seizure and CNS indications[1][4][7][10].
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