Company intelligence / Profile preview

H4 Orphan Pharma

Dijon, Bourgogne-Franche-Comté, Franceh4orphanpharma.com ↗
Ownership
Private
Employees
~9
Development stage
Preclinical
01

Overview

H4 Orphan Pharma SAS is a French biotech/pharmaceutical SME founded in Dijon in 2016. The company specializes in developing small molecule drugs—specifically multifunctional ligands—for the treatment of orphan fibrotic diseases. Its two lead preclinical candidates target idiopathic pulmonary fibrosis and dry eye disease associated with Sjögren’s syndrome. Both compounds act via stimulation/modulation of the CFTR protein. The company owns its intellectual property outright and invests heavily in R&D (~83% of resources). In January 2025, it licensed an asset to TheraVet SA/EGEIRO Pharma for further development in idiopathic pulmonary fibrosis.

Therapeutic areas
OphthalmologyPulmonologyRare Diseases
Modalities
Small moleculesMultifunctional ligands
Industry
Biotech
02

Drug pipeline

1 asset

554-002

Unknown
03

Partnerships

License agreement with TheraVet SA/EGEIRO Pharma for IPF program as part of a reverse takeover transaction valued at €14 million.Past exclusive merger negotiations with Cerenis Therapeutics were announced but not confirmed completed as of latest available data.

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