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HavaH Therapeutics' lead program T+Ai™, a subcutaneous extended-release pellet combining testosterone and anastrozole, has demonstrated statistically significant reductions in mammographic breast density and background parenchymal enhancement—both indicators of reduced risk for progression to invasive disease—in open-label cohort studies. The company’s ongoing Phase 2 RECAST DCIS study aims to prevent progression of ductal carcinoma in situ to invasive breast cancer. Over 3,500 woman-years of clinical exposure have been accumulated with favorable safety data.[1][2][3]
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