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Karyopharm has one FDA-approved product, XPOVIO (selinexor), approved in three oncology indications in the U.S. The company is conducting Phase 3 trials for myelofibrosis (SENTRY trial, top-line results expected March 2026) and endometrial cancer (XPORT-EC-042 trial, top-line results expected mid-2026)[7].
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