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Healis Therapeutics is developing CKDB‑501A, a botulinum toxin type A neuromodulator, as a novel treatment for major depressive disorder and other neuropsychiatric conditions. The company has reported promising results from randomized controlled trials of glabellar BoNT/A injections for MDD. Its strategic partnership with CKD Bio provides access to clinical-stage BoNT/A assets that have demonstrated non-inferiority to BOTOX® in aesthetic indications and are now being advanced into psychiatric indications through collaborations with Massachusetts General Hospital and Harvard Medical School affiliates[4][5][6][8].
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