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Helion Biotech has a Phase II-ready replacement therapy with recombinant human MBL (rhMBL) for treating inherited immune defects. The therapy is supported by over 10 independent clinical publications since 2006 linking MBL deficiency to high risk of neonatal infection and sepsis. A complete US regulatory dossier enables direct entry into a Phase II clinical trial, and additional expansion to other immunocompromised indications is proposed.
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