Company intelligence / Profile preview
Helocyte
Los Angeles, California, USAhelocyte.com ↗
- Ownership
- Private
- Development stage
- Phase 2
01
Overview
Helocyte’s lead program, Triplex—a recombinant Modified Vaccinia Ankara viral vector expressing three immunodominant human CMV antigens—has demonstrated safety, strong immunogenicity, and efficacy in a completed first-in-patient Phase II study for allogeneic hematopoietic stem cell transplantation. The company has initiated or planned additional Phase II trials targeting solid organ transplants and HIV/CMV co-infection. No approved immunotherapy currently exists for congenital or post-transplantation CMV prevention/control.
- Therapeutic areas
- OncologyInfectious Diseases
- Modalities
- Prophylactic vaccinesTherapeutic vaccinesRecombinant vector vaccinesImmunotherapies (T cell-based)
- Industry
- Biotech
02
Drug pipeline
1 asset03
Partnerships
City of Hope National Medical Center—exclusive licensee/collaborator on Triplex development; option agreement to combine Triplex with bispecific CAR-T therapy targeting both HIV and CMV.
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