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HighPass Bio

Cambridge, Massachusetts, United Stateshighpassbio.com ↗
Ownership
Private
Development stage
Phase 1
01

Overview

HighPass Bio’s lead program is a Phase 1 clinical trial evaluating adoptive immunotherapy with CD8+ and CD4+ donor memory T cells transduced to express an HA‑1-specific TCR for patients with relapsed leukemia following allogeneic HSCT. Initial patients have been dosed, but the trial is currently listed as suspended. The approach aims to treat or prevent post-transplant leukemic relapse by targeting the minor histocompatibility antigen HA‑1 on leukemic cells

Therapeutic areas
OncologyHematology
Modalities
T cell receptor (TCR)-engineered T cellsAdoptive cell therapyEngineered memory T cells (CD8+ and CD4+)
Industry
Biotech
02

Drug pipeline

1 asset

HA-1 TCR T cell therapy

Phase 1
Indications
Post-transplant leukemia relapse
03

Partnerships

ElevateBio BaseCamp provides process development and manufacturing support for cell/gene therapies.Originated from research at Fred Hutchinson Cancer Research Center.

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