Hino Seiyaku

Hino Seiyaku is a traditional Japanese pharmaceutical company based in Nagano Prefecture, specializing in the manufacture and sale of herbal medicines. The company is most famous for its flagship product, Hyakusogan, a gastrointestinal medicine derived from the bark of the Phellodendron amurense tree. With a history tracing back to the Edo period, Hino Seiyaku combines centuries-old Kampo (traditional Japanese medicine) knowledge with modern manufacturing standards. Their product line focuses primarily on digestive health, offering natural remedies for symptoms such as indigestion, overeating, and stomach discomfort. In addition to its core pharmaceutical business, the company produces various health supplements and traditional ointments. Hino Seiyaku remains a key representative of the regional pharmaceutical heritage of the Kiso region in Japan.