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Holistick Medical is a private French medtech company developing minimally invasive devices for structural heart defect repair. Its lead focus is a catheter-delivered, nonmetallic, flexible adhesive device for closure of patent foramen ovale (PFO), intended to reduce recurrent stroke risk in selected patients. The company positions its approach as less traumatic than conventional metallic occluders, with a small footprint and preservation of septal access for potential future cardiac interventions. Holistick Medical licenses foundational technology originating from Harvard and collaborators and has raised venture and non-dilutive funding to advance preclinical development toward first-in-human readiness. The company operates primarily from Paris and has also referenced R&D activity in the Boston area.
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