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City of Hope is a world-renowned independent biomedical research and treatment center and a National Cancer Institute-designated comprehensive cancer center. Founded in 1913 and headquartered in Duarte, California, the institution is a major engine of innovation in the biotechnology industry, having developed the foundational technology for synthetic human insulin and numerous blockbuster monoclonal antibodies, including Herceptin, Rituxan, and Avastin. City of Hope maintains an extensive internal pipeline of over 50 active clinical trials, with a particular leadership position in CAR-T cell therapies for both hematologic and solid tumors. The organization operates its own GMP-compliant manufacturing facilities for biologics and cell therapies, facilitating the rapid translation of laboratory discoveries into clinical applications. Through its Beckman Research Institute and subsidiaries like TGen, City of Hope continues to drive advancements in precision medicine, diabetes research, and gene therapy.
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