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The company has developed a novel CAR T-cell construct with a unique, patented co-stimulatory domain that produces stronger anti-cancer activity in the laboratory than existing second-generation CAR T-cells. Preliminary clinical data suggests an improved safety profile with fewer side effects than competing CAR T-cell treatments. Phase I trials have been conducted for various cancers, and results of the ENABLE trial in New Zealand were due to be published in 2023.
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