Hypha Discovery

Hypha Discovery provides specialist contract research services to pharmaceutical and agrochemical companies worldwide, focusing on the scalable synthesis, purification, and structural elucidation of drug metabolites—including difficult-to-synthesize phase I/II metabolites such as oxidized forms and glucuronides—as well as natural product derivatives. Their proprietary platforms include recombinant enzyme kits like PolyCYPs® for cytochrome P450-mediated metabolism studies and PolyUGTs kits for glucuronidation. They also offer advanced analytical capabilities including cryoprobe NMR spectroscopy. The company does not develop its own therapeutic pipeline but enables R&D across a wide range of indications by providing reference standards, impurity characterization, custom biosynthesis solutions, and more.