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i-Cordis

Baltimore, Maryland, United States
Ownership
Private
Development stage
Other
01

Overview

i-Cordis is developing pegydone, a PEGylated derivative of pirfenidone, as an immunomodulatory oral small molecule for heart failure with preserved ejection fraction (HFpEF); supported by completed rodent proof‑of‑concept studies and a Phase II NHLBI SBIR grant to complete critical preclinical de‑risking prior to IND filing.[1][2][4][6]

Therapeutic areas
CardiovascularPulmonologyRare Diseases
Modalities
Small molecule
Industry
Biotech
02

Drug pipeline

1 asset

Pegydone

Preclinical
03

Partnerships

Johns Hopkins University (laboratory of Dr. Luigi Adamo for preclinical cardiac immunology and HFpEF models)[1][6]Washington University in St. Louis (foundational IP on pegydone / PEGylated pirfenidone; patent application filed by WashU in 2018)[2]

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