Iatrogenix

Iatrogenix was a biotechnology company based in South San Francisco, California, that specialized in the development of therapeutics for macrophage-mediated and iatrogenic diseases. Founded by Dr. Michael S. McGrath, a researcher from the University of California, San Francisco, the company focused on the role of activated macrophages in chronic inflammation, oncology, and viral infections. Its primary research objective was to identify and target specific macrophage subsets that drive disease progression in conditions such as HIV-associated dementia and various solid tumors. The company leveraged a platform designed to modulate macrophage activity to restore immune balance or eliminate diseased cells. Iatrogenix is currently inactive, and its foundational research has largely transitioned into academic projects or subsequent ventures led by its founders.