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IAVI is a global non-profit scientific research organization focused on developing vaccines and antibodies for HIV, tuberculosis, and emerging infectious diseases. In South Africa, IAVI operates through a robust network of clinical research centers, conducting pivotal trials to address regional health priorities. The organization is well-known for its work on the MTBVAC tuberculosis vaccine candidate and various germline-targeting HIV vaccine strategies. IAVI utilizes advanced technologies, including the recombinant Vesicular Stomatitis Virus (rVSV) platform and mRNA delivery systems in collaboration with industry partners. Their mission emphasizes ensuring that life-saving biomedical innovations are affordable and accessible to populations in low- and middle-income countries. By partnering with local institutions like the Aurum Institute and the University of the Witwatersrand, IAVI South Africa strengthens clinical research capacity across the region.
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