Company intelligence / Profile preview
IGM Biosciences
Mountain View, California, United Statesigmbio.com ↗
- Ownership
- Public · IGMS
- Employees
- ~55
- Development stage
- Other
01
Overview
IGM Biosciences was developing novel bispecific IgM antibody drugs for autoimmune diseases and cancer. Its two main autoimmune candidates—imvotamab and IGM‑2644—were both discontinued in January 2025 after Phase Ib data showed insufficient B cell depletion in rheumatoid arthritis and lupus patients. The company also minimized spending on its oncology program aplitabart due to strategic refocus. As a result, IGM laid off approximately three quarters of its workforce and began evaluating strategic alternatives including potential sale or merger.
- Therapeutic areas
- OncologyImmunologyNeurology
- Modalities
- IgM antibodiesBispecific T cell engagersIgA antibodies
- Industry
- Biotech
02
Drug pipeline
7 assets6 more assets in the full pipeline.
03
Partnerships
Sanofi – major partnership since March/April 2022 focused on immunology/inflammation drug development using IGM’s technology; Sanofi paid $150 million upfront with up to $6 billion in milestones possible. This partnership remains the only significant revenue source post-pipeline discontinuation.
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