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Imbria Pharmaceuticals

Boston, Massachusetts, United Statesimbria.com ↗

Ownership: Private
Development stage: Phase 2

Overview

Imbria’s lead candidate ninerafaxstat has demonstrated positive results in multiple Phase 2 clinical trials across three indications—non-obstructive hypertrophic cardiomyopathy (nHCM), stable angina, and HFpEF. In nHCM patients, it was the first investigational drug to show improvement in functional measures by exercise testing and patient-reported symptoms. In HFpEF patients, it improved cardiac energetics and physical limitations. The drug has been well tolerated to date.

Therapeutic areas: Cardiovascular
Modalities: small molecules (notably partial fatty acid oxidation inhibitors)
Industry: Biotech

Drug pipeline

2 assets

ninerafaxstat

1 more asset in the full pipeline.

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Partnerships

Cytokinetics participated as an investor; no major disclosed pharma partnerships beyond investment syndicate.

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