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Immutep’s lead candidate, eftilagimod alpha (efti), is in a pivotal Phase 3 trial in first-line non-small cell lung cancer in combination with pembrolizumab and chemotherapy; multiple Phase 2 and earlier trials in various solid tumors and autoimmune diseases are ongoing. The company has licensed out certain LAG-3 pipeline assets to major pharma partners with external programs in both oncology and autoimmune diseases. Efti has shown improved response rates and robust safety in several completed and ongoing studies.[1][4][2]
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