topotecan
Phase 1- Indications
- High grade glioma
Company intelligence / Profile preview
Infuseon Therapeutics
Cleveland, Ohio, United Statesinfuseontherapeutics.com ↗
- Ownership
- Private
- Development stage
- Other
01
Overview
Infuseon Therapeutics has enabled the direct delivery of chemotherapeutics (e.g., topotecan, OS2966) to the brain using the Cleveland Multiport Catheter. Early-phase studies demonstrated effective device-based administration to tumor-infiltrated brain; the company has completed a Phase 1 pilot with topotecan and OS2966 in high-grade glioma. MRI-monitored infusions showed broad coverage and reliable delivery. The OS2966 trial was terminated; further clinical development updates are not evident after 2024.[3][4][5]
- Therapeutic areas
- OncologyNeurology
- Modalities
- DeviceSmall moleculeBiologic
- Industry
- Therapeutic Medical Devices
02
Drug pipeline
1 asset03
Partnerships
OncoSynergy (collaboration on OS2966 in glioblastoma)Parker-Hannifin Corporation (medical device manufacturing partner)
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