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ICT’s lead program, GCC19CART, has shown promising results in relapsed/refractory metastatic colorectal cancer (mCRC), with a reported objective response rate (ORR) of up to 80% at higher dose levels and median overall survival exceeding 17 months in early US trials. The company’s CoupledCAR® platform aims to overcome the challenges of CAR-T therapy for solid tumors. Additional pipeline candidates are being developed for other solid tumor indications such as prostate cancer[1][2].
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